Adherence to guidelines for glucose assessment in starting second-generation antipsychotics

Marsha A. Raebel, Robert Penfold, Ann W. McMahon, Marsha Reichman, Susan Shetterly, Glenn Goodrich, Susan Andrade, Christoph U. Correll, Tobias Gerhard 11/01/2014

OBJECTIVES: In 2003, the US Food and Drug Administration issued warnings about hyperglycemia and diabetes with second-generation antipsychotics (SGAs); guidelines have recommended metabolic screening since 2004. However, little is known of contemporary practices of glucose screening among youth initiating SGAs. Our objective was to evaluate baseline glucose assessment among youth in the Mini-Sentinel Distributed Database starting an SGA. METHODS: The cohort included youth ages 2 through 18 newly initiating SGAs January 1, 2006, through December 31, 2011, across 10 sites. Baseline glucose was defined as fasting/random glucose or hemoglobin A1c (GLU) measurement occurring relative to first SGA dispensing. Differences in GLU assessment were evaluated with χ2 tests and logistic regression.

Methodological considerations in observational comparative effectiveness research for implantable medical devices: An epidemiologic perspective

Jessica J. Jalbert, Mary Elizabeth Ritchey, Xiaojuan Mi, Chih Ying Chen, Bradley G. Hammill, Lesley H. Curtis, Soko Setoguchi Iwata 11/01/2014

Medical devices play a vital role in diagnosing, treating, and preventing diseases and are an integral part of the health-care system. Many devices, including implantable medical devices, enter the market through a regulatory pathway that was not designed to assure safety and effectiveness. Several recent studies and high-profile device recalls have demonstrated the need for well-designed, valid postmarketing studies of medical devices.

Addressing health and well-being of U.S. Chinese older adults through community-based participatory research: Introduction to the pine study

Xinqi Dong 11/01/2014

The PINE Study-the Population Study of Chinese Elderly in Chicago, sōng nián yán jiū) is a population-based epidemiological study of U.S. Chinese older adults in the greater Chicago area with primary aims to examine their health status and well-being.

Do the definitions of elder mistreatment subtypes matter? Findings from the PINE study

Xinqi Dong 11/01/2014

Background: Elder mistreatment (EM) is a pervasive public health issue and is associated with morbidity and premature mortality. This study aimed to examine how the prevalence of EM and its subtypes vary using different definitions among U.S. Chinese older adults.

Perceived barriers and facilitators to implement elder abuse intervention for victims and perpetrators: Views from US Chinese older adults

Xinqi Dong, E. Shien Chang, Esther Wong, Melissa A. Simon 10/07/2014

Purpose – The purpose of this paper is to explore US Chinese older adults’ views regarding elder abuse interventions in order to understand barriers and facilitators of help-seeking behaviors.

A psychometric assessment of the psychological and social well-being indicators in the PINE study

E. Shien Chang, Todd Beck, Melissa A. Simon, Xinqi Dong 10/01/2014

Objective: This report aims to establish the reliability and validity of five psychological and social well-being indictors in their applications to a U.S. Chinese aging population.

Demographic characteristics of U.S. Chinese older adults in the Greater Chicago area: Assessing the representativeness of the PINE study

Melissa A. Simon, E. Shien Chang, Kumar Bharat Rajan, Mary Jane Welch, Xinqi Dong 10/01/2014

Objective: We aimed to assess the representativeness of the demographic characteristics of the PINE study to the Chinese aging population in the Greater Chicago area.

Prevalence and correlates of elder mistreatment in a community-dwelling population of U.S. Chinese older adults

Xinqi Dong, Ruijia Chen, Terry Fulmer, Melissa A. Simon 10/01/2014

Objective: This study aimed to examine the prevalence and correlates of elder mistreatment among U.S. Chinese older adults. Method: Data were drawn from the Population-Based Study of ChINese Elderly (PINE) study, a population-based epidemiological survey of 3,159 U.S. Chinese older adults in the Greater Chicago area.

Antipsychotic medication use in nursing homes: A proposed measure of quality

Judith A. Lucas, Sujoy Chakravarty, John R. Bowblis, Tobias Gerhard, Ece Kalay, Eun Kwang Paek, Stephen Crystal 10/01/2014

Objective: The potential misuse of antipsychotic medications (APMs) is an ongoing quality concern in nursing homes (NHs), especially given recent black box warnings and other evidence regarding the risk of APMs when used in NH populations. One mechanism regulators could use is public reporting of APM use by NHs; however, there is currently no agreed-upon measure of guideline-inconsistent APM use. In this paper, we describe a proposed measure of quality of APM use that is based on Centers for Medicare and Medicaid Services (CMS) Interpretive Guidelines, Food and Drug Administration (FDA) indications for APMs, and severity of behavioral symptoms.

A population-based study of physical function and risk for elder abuse reported to social service agency: Findings from the Chicago health and aging project

Xinqi Dong, Melissa Simon, Denis Evans 10/01/2014

We examined the association between physical function and the risk for reported elder abuse. In the Chicago Health and Aging Project (N = 8,932), 238 participants had reported elder abuse.

Lifestyle factors as predictors of nonadherence to statin therapy among patients with and without cardiovascular comorbidities

Heli Halava, Maarit Jaana Korhonen, Risto Huupponen, Soko Setoguchi Iwata, Jaana Pentti, Mika Kivimäki, Jussi Vahtera 09/02/2014

Methods: We included 9285 participants from the Finnish Public Sector Study who began statin therapy after completing the survey. We linked their survey data with data in national health registers. We used prescription dispensing data to determine participants’ nonadherence to statin therapy during the first year of treatment (defined as < 80% of days covered by filled prescriptions). We used logistic regression to estimate the association of several lifestyle factors with nonadherence, after adjusting for sex, age and year of statin initiation.

Use of combination antihypertensive therapy initiation in older americans without prevalent cardiovascular disease

Xiaojuan Li, Wendy Camelo Castillo, Til Stürmer, Virginia Pate, Christine L. Gray, Ross J. Simpson, Soko Setoguchi Iwata, Laura C. Hanson, Michele Jonsson Funk 09/01/2014

Objectives To describe new users of antihypertensive medications and identify predictors of combination therapy initiation in older Americans. Design Retrospective observational cohort study. Setting Population-based study using U.S. Medicare fee-for-service healthcare claims (2007-2010). Participants Medicare beneficiaries aged 65 and older with no recent diagnoses, procedures, or medications for cardiovascular disease who newly initiated an antihypertensive therapy (n = 275,493; 210,605 initiated monotherapy, 64,888 initiated combination therapy).

Validity of claims-based stroke algorithms in contemporary medicare data: Reasons for geographic and racial differences in stroke (REGARDS) study linked with medicare claims

Hiraku Kumamaru, Suzanne E. Judd, Jeffrey R. Curtis, Rekha Ramachandran, N. Chantelle Hardy, J. David Rhodes, Monika M. Safford, Brett M. Kissela, George Howard, Jessica J. Jalbert, Thomas G. Brott, Soko Setoguchi Iwata 07/01/2014

Background-The accuracy of stroke diagnosis in administrative claims for a contemporary population of Medicare enrollees has not been studied. We assessed the validity of diagnostic coding algorithms for identifying stroke in the Medicare population by linking data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study to Medicare claims.

Temporal trends in treatment outcomes for HIV-1 and HIV-2-infected adults enrolled in Côte d’Ivoire’s national antiretroviral therapy program

Andrew F. Auld, Kunomboa A. Ekra, Ray W. Shiraishi, Moise Z. Tuho, Joseph S. Kouakou, Fayama Mohamed, Virginie Ettieg̀ne-Traoré, Jennifer Sabatier, Joseph Essombo, Georgette Adjorlolo-Johnson, Richard Marlink, Tedd V. Ellerbrock 05/27/2014

Background: In Côte d’Ivoire during 2004-2007, numbers of ART enrollees increased from <5,000 to 36,943. Trends in nationally representative ART program outcomes have not yet been reported.

Influence of healthy candidate bias in assessing clinical effectiveness for implantable cardioverter-defibrillators: Cohort study of older patients with heart failure open access

Soko Setoguchi Iwata, Lynne Warner Stevenson, Garrick C. Stewart, Deepak L. Bhatt, Andrew E. Epstein, Manisha Desai, Lauren A. Williams, Chih Ying Chen 05/08/2014

Objective: To assess the potential contribution of unmeasured general health status to patient selection in assessments of the clinical effectiveness of implantable cardioverter-defibrillator (ICD) therapy. Design: Retrospective cohort study. Setting: Linked data from an ICD registry, heart failure registry, and Medicare claims data for ICDs implanted in 2005 through 2009.

Association of depressive symptomatology and elder mistreatment in a U.S. Chinese population: Findings from a community-based participatory research study

Xinqi Dong, E. Shien Chang, Esther Wong, Bernarda Wong, Melissa A. Simon 01/02/2014

Elder mistreatment (EM) is associated with increased morbidity and mortality. The objective of this study is to examine the association between depressive symptoms and EM in a U.S. Chinese population.

Community-campus partnership in action: Lessons learned from the dupage county patient navigation collaborative

Athena T. Samaras, Kara Murphy, Narissa J. Nonzee, Richard Endress, Shaneah Taylor, Nadia Hajjar, Rosario Bularzik, Carmi Frankovich, Xinqi Dong, Melissa A. Simon 01/01/2014

Background: Using community-based participatory research (CBPR), the DuPage County Patient Navigation Collaborative (DPNC) developed an academic campus-community research partnership aimed at increasing access to care for underserved breast and cervical cancer patients within DuPage County, a collar county of Chicago. Given rapidly shifting demographics, targeting CBPR initiatives among underserved suburban communities is essential.

Decline in cognitive function and elder mistreatment: Findings from the Chicago Health and Aging Project

Xinqi Dong, Melissa Simon, Todd Beck, Denis Evans 01/01/2014

Objective: This study aimed to examine the longitudinal association between decline in cognitive function and elder mistreatment (EM). Methods: Chicago Health and Aging Project (CHAP) is an epidemiologic study conducted in a geographically defined community (N = 6,159).

Elder abuse: Research, practice, and health policy. the 2012 GSA Maxwell pollack award lecture

Xinqi Dong 01/01/2014

Elder abuse, also called elder mistreatment or elder maltreatment, includes psychological, physical, and sexual abuse, neglect (caregiver neglect and self-neglect), and financial exploitation.

Elder abuse and dementia: A review of the research and health policy

Xinqi Dong, Ruijia Chen, Melissa A. Simon 01/01/2014

Older adults with dementia may be at high risk for abuse, but the topic has not been well studied. We conducted a literature review to examine the relationships between elder abuse and dementia.